Well...it "looks" like everything went well except for one thing...
I moved my OneDrive local folder to my 128GB SD card last week (I've got it setup for BitLocker and to automatically unlock on sign in), and although I hadn't had any issues before, for some reason after the update, I started having issues with the Office Document Upload Center. Now, I've fought that thing before so I know how to repair the cache and all that jazz, but that wasn't the "real" issue here. Something changed in the timing of things on logon and it appears that the SD card wasn't "ready" when the Upload Center started. So...into Task Scheduler I go, and I modified the startup trigger to delay by 3 minutes. Now when I boot I no longer get the dreaded "Microsoft Office cache encountered a problem"-crap on every boot.