I'm having problems with some menus on Autocad. Some letters are very small and others are really big as you can see on the attached file.
Can I do something to fix this?.
Yeah, looks like issues with Autocad and Windows 10 screen scaling. As mentioned, try setting your screen scaling to 100% (down from probably 200%) and see if that fixes it.
I had to do the Manifest file route for a program I needed to use that wasn't scaling correcty on the Surface High DPI display. I found the info on this site that was working around the issue with Photoshop. Adobe App Scaling on High DPI Displays (FIX) | Dan Antonielli
I was surprised yesterday because when the Surface updated all the fonts where just perfect but today all has come back to the old odd fonts. I can't understand why.