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OK. So using DOSBox did not work as apparently, "Many USB serial ports do not support a 5 bits per byte configuration...". I have no idea what that means, but I lifted that little phrase from this site: DOSBox DOS Emulator / Patches / #249 USB Serial work-around which apparently has a fix for...

Thanks for the reply Jeff, Unfortunately this application is used to connect to a medical device - essentially robotics. I connect via USB to 9 pin connector and then to a 25 pin connector (I think its 25 pin...). No updated program is available. I did some more digging and read about DOSbox...

I've encountered an issue with running a particular DOS based application on my Surface Pro. Although I have set the properties of the application to run in Windows XP compatibility mode, and have allowed it to Run As Administrator, the Surface Pro returns the following error: "Windows cannot...